BDBM135814 US10085990, Example 33::US10568888, Example 33::US8853226, 33::US9393245, 33::US9833457, 33

SMILES CCn1c(=O)n(C2CCCC2)c2c3cccc(C(C)C)c3ncc2c1=O

InChI Key InChIKey=IWWGJHDCEUWDTE-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 135814   

TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B2)(Homo sapiens (Human))
Vtv Therapeutics

US Patent
LigandPNGBDBM135814(US10085990, Example 33 | US10568888, Example 33 | ...)
Affinity DataIC50:  1.24E+4nMT: 2°CAssay Description:The assay buffer was prepared by diluting 5× supplied Tween-based buffer in 1:5 in water to make 1× buffer. Add desired additive to buffe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B2)(Homo sapiens (Human))
Vtv Therapeutics

US Patent
LigandPNGBDBM135814(US10085990, Example 33 | US10568888, Example 33 | ...)
Affinity DataIC50:  1.24E+4nMAssay Description:A TR-FRET-based phosphodiesterase assay kit from Molecular Devices was used to test whether these compounds were indeed direct inhibitors of the PDE4...More data for this Ligand-Target Pair
In DepthDetails US Patent